AMLOPIN M 25 TAB

What is AMLOPIN?

• AMLOPIN is the combination of Amlodipine Besylate (calcium channel blockers) and Metoprolol Tartarate (Beta blockers)

What AMLOPIN is used for?

• It is used in the treatment of hypertension and angina pectoris
• It prevents death due to heart attacks

Talk to your doctor before taking this medicine If you

• Are allergic to AMLOPIN
• Suffer with heart conduction or rhythm problems, heart failure, blocked blood vessels
• Suffer from a tight, painful feeling in the chest in periods of rest (Prinzmetal’s angina)
• Are suffering from narrowing of the aortic heart valve (aortic stenosis)
• Suffer with untreated phaeochromocytoma (high blood pressure due to a tumor near the kidney)
• Suffer from increased acidity of the blood (metabolic acidosis)
• Have low blood pressure
• Have or have had breathing difficulties or asthma including COPD
• Suffer with diabetes associated with frequent episodes of low blood sugar (hypoglycaemia)
• Have liver or kidney disease or failure
• Have difficulties in passing urine
• Have low levels of potassium (hypokalaemia) or sodium (hyponatraemia) in your blood
• Have high levels of calcium (hypercalcaemia)
• Suffer with gout due to high levels of uric acid
• Have or have suffered from psoriasis (severe skin rashes)
• Have myasthenia gravis
• Are going to have an operation or an anaesthetic, please tell your doctor that you are taking AMLOPIN tablets, as your heart beat might slow down too much

Do not take AMLOPIN if you are already taking:

• Other antihypertensives as injection especially verapamil, diltiazem or disopyramide.
• Monoamine Oxidase Inhibitors (MAOIs) for depression
• Cimetidine (to treat stomach ulcers)
• Hydralazine, Clonidine or Prazosin (to treat high blood pressure)
• Amiodarone and Propafenone (for irregular heart rhythm)
• Tricyclic or SSRI antidepressants (to treat depression)
• Barbiturates (to treat epilepsy)
• Phenothiazines (for mental illness)
• Anaesthetics such as cyclopropane or trichloroethylene
• Aldesleukin (to treat some cancers, particularly cancer of the kidney)
• Alprostadil (to treat erectile dysfunction)
• Anxiolytics or hypnotics (e.g. temazepam, nitrazepam, diazepam)
• Indometacin or celecoxib (Non-Steroidal Anti-Inflammatory Drugs (NSAIDs))
• Rifampicin (antibiotic) or Terbinafine or Ketoconazole and Itraconazole (antifungal)
• Cocaine
• Corticosteroids (e.g. hydrocortisone, prednisolone)
• Other beta-blockers e.g. eye drops.
• Adrenaline (epinephrine) or Noradrenaline (norepinephrine), used in anaphylactic shock or other sympathomimetics
• Medicines used to treat diabetes
• Lidocaine (a local anaesthetic)
• Moxisylyte (used in Raynaud’s syndrome)
• Mefloquine (to treat malaria)
• Tropisetron (to prevent nausea and vomiting)
• Xanthines such as Aminophylline or Theophylline (to treat asthma)
• Medicines to treat migranes such as Ergotamine
• Cardiac glycosides e.g. Digoxin (to treat heart conditions)
• Hydroxychloroquine (to treat rheumatoid arthritis)
• Diphenydramine (sedative antihistamine).

Directions & For Use

• Always take this medicine exactly as your doctor has told you
• You should check with your doctor or pharmacist if you are not sure
• Swallow the medicine with a glass of water

High blood pressure

• Initially 100mg metoprolol tartrate daily. The dose may be increased to 200mg daily in single or divided doses

Angina

• 50-100mg metoprolol tartrate two or three times daily

Irregular heartbeats (arrhythmia)

• 50mg metoprolol tartrate two or three times daily. The dose may be increased to 300mg daily in divided doses

Heart attacks

• 50mg metoprolol tartrate every six hours. The usual maintenance dose is 200mg daily in divided doses. The medicine should be taken for at least 3 months

If you take more AMLOPIN

• If you or someone else has taken too much AMLOPIN, contact your nearest hospital casualty department

If you forget to take AMLOPIN

• If you forget to take a dose, take it as soon as you remember, unless it is nearly time for your next dose. Do not take a double dose to make up for a forgotten dose

If you stop taking AMLOPIN

• Do not suddenly stop taking this medicine as this may cause worsening of heart failure and increase the risk of heart attack. Only change the dose or stop the treatment in consultation with your doctor